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July 6, 2025
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January 5, 2026
Published
January 13, 2026
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Abstract

This animal study evaluates the influenc of platelet-rich fibrin (PRF) on bone regeneration around titanium dental implants in a diabetic rabbit model. Sixteen rabbits were divided into control and PRF-treated groups, with implants placed bilaterally in the femur. After 8 weeks, histological and histomorphometric analyses were performed. The PRF group exhibited significantly greater bone-to-implant contact and new bone volume compared to controls. These results Suggest that PRF may enhance early osseointegration in compromised healing conditions such as diabetes. The findings support the potential use of autologous biologics in implant dentistry for medically compromised patients.

Keywords

Dental implants platelet-rich fibrin bone regeneration diabetes histomorphometry

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Copyright (c) 2026 Ameer Hamdi AL-Ameedee, Z Salameh, Ali Ameer AL-Ameedee (Author)

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Ameer Hamdi AL-Ameedee, Z Salameh and Ali Ameer AL-Ameedee (2026) “Histomorphometric Assessment of Peri-Implant Bone Formation Using Platelet-Rich Fibrin in Diabetic Rabbits”, Future Dental Research, 3(2), pp. 34–48. doi:10.57238/fdr.2025.152576.1017.
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How to Cite

Ameer Hamdi AL-Ameedee, Z Salameh and Ali Ameer AL-Ameedee (2026) “Histomorphometric Assessment of Peri-Implant Bone Formation Using Platelet-Rich Fibrin in Diabetic Rabbits”, Future Dental Research, 3(2), pp. 34–48. doi:10.57238/fdr.2025.152576.1017.

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