Main Article Content
Abstract
Dental caries is one of the most common health problems in the world. It is caused by a number of things, such as what you eat, the bacteria in your mouth, and the acidity (pH) levels around your teeth. When you eat sweet meals, some bacteria, such Streptococcus mutans and Lactobacillus, can break down the sugars and create acids. These acids steadily eat away at the enamel that protects our teeth. Not getting enough vital minerals, including calcium, Phosphorus, vitamins C and D, and other things can make our teeth and gums weaker, which makes them more susceptible to get harmed. The relationship between salivary characteristics, such as salivary pH, and plaque biofilms will affect how we treat dental caries as a whole. For dental caries, this involves the consistent disruption of the oral plaque biofilm by mechanical oral hygiene, along with dietary modifications to reduce exposure to fermentable carbohydrates. Eating and drinking too many sweet things can make your mouth more acidic, which can hurt your gums and enamel. At the same time, not getting enough vitamins C and D might make it harder for the body to heal and fight illnesses. Saliva and bacteria in the mouth are the two main things that cause dental caries. It has been shown that there is a link between pH levels and the number of cavities, as well as the effects of local and systemic factors and how changes in pH levels affect tooth structure. An acidic mouth environment causes demineralization and remineralization to happen at different rates, and it also causes more acid-loving bacteria to grow. This article explains how diet, saliva pH, and plaque all work together to affect oral health. It stresses the importance of good nutrition and everyday care for keeping teeth healthy.
Keywords
Article Details
Copyright (c) 2025 Zaman Kareem Hanan, Adnan abed azeez alazraqi, Shamam K. Oudah (Author)

This work is licensed under a Creative Commons Attribution 4.0 International License.
How to Cite
References
- Bell E. Strategy for the selection of scaffolds for tissue engineering. Tissue Eng. 1995 Jun 1;1(2):163-79. doi: 10.1007/s00586-008-0745-3.
- Marsh PD. In sickness and in health—what does the oral microbiome mean to us? Clinical Oral Investigations. 2018;22(3):1137–1144.doi:10.1007/s00784-018-2464-2
- Simón-Soro A, Mira A. Solving the etiology of dental caries. Trends in Microbiology.2015;23(2):76–82. doi:10.1016/j.tim.2014.10.010
- Vellore G, Arzreanne AR. Saliva as a diagnostic tool for assessment of dental caries. Archives of Orofacial Sciences. 2006;1:57–59.https://publisher.uthm.edu.my/ojs/index.php/aos/article/view/289
- Ruby JD, Goldner M. Nature of symbiosis in oral biofilms. Oral Diseases. 2007;13(1):11–18.doi:10.1111/j.1601-0825.2006.01305.x
- Tanner ACR, et al. Microbiota of dental caries. Journal of Dental Research. 2016;95(6):624–630.doi:10.1177/0022034516644649
- Bowen WH, Koo H. Biology of Streptococcus mutans–derived glucosyltransferases. Caries Research. 2011;45(1):69–86. doi:10.1159/000324598
- Maria H, Fatmasari D. Relationship of saliva pH and DMF-T index in metadon housing therapy in Yogyakarta City. Jurnal Riset Kesehatan. 2020;9(1):28–32.doi:10.31983/jrk.v9i1.5641
- Lin YTJ, Lin YT. Influence of dental plaque pH on caries status and salivary microflora in children following comprehensive dental care under general anesthesia. Journal of Dental Sciences. 2018;13(1):8–12.doi:10.1016/j.jds.2017.05.002
- Ferrer MD, Pérez S, Lopez AL, et al. Evaluation of clinical, biochemical and microbiological markers related to dental caries. International Journal of Environmental Research and Public Health. 2021;18(11):6049.doi:10.3390/ijerph18116049
- Hajishengallis E, Parsaei Y, Klein MI, Koo H. Advances in the microbial etiology and pathogenesis of early childhood caries. Molecular Oral Microbiology. 2017;32(1):24–34.doi:10.1111/omi.12152
- Bowen WH, Burne RA, Wu H, Koo H. Oral biofilms: pathogens, matrix, and polymicrobial interactions in microenvironments. Trends in Microbiology. 2018;26(3):229–242. doi:10.1016/j.tim.2017.09.008
- Saxena P, Bhatnagar M, Bansal R, et al. Association of dermatoglyphic patterns with DMFT score, salivary pH and plaque index score. Journal of Forensic Dental Sciences. 2022;12:81–88.doi:10.18311/jfds/12/2/2020.610
- Aranibar Quiroz EM, et al. Relationship between plaque pH and different caries-associated variables. Caries Research. 2014;48(2):147–153.doi:10.1159/000355614
- Scardina GA, Messina P. Good oral health and diet. Journal of Biomedicine and Biotechnology. 2012;2012:720692.doi:10.1155/2012/720692
- Palmer CA, Boyd LD. Diet and nutrition in oral health. Journal of the California Dental Association. 2009;37(5):357–366.https://pubmed.ncbi.nlm.nih.gov/19473145
- Nishida M, Grossi SG, Dunford RG, et al. Dietary vitamin C and the risk for periodontal disease. Journal of Periodontology. 2000;71(8):1215–1223.doi:10.1902/jop.2000
- Duggal MS, van Loveren C. Dental considerations for dietary counselling. International Dental Journal. 2001;51(6):408–412.doi:10.1002/j.1875-595X.2001.tb00850.x
- Bradshaw DJ, Lynch RJ. Diet and the microbial aetiology of dental caries. International Dental Journal. 2013;63(Suppl 2):64–72.doi:10.1111/idj.12082
- Dawes C. Role of saliva and salivary diagnostics in oral health advancement. Journal of Dental Research. 2019;98(2):133–141.doi:10.1177/0022034518817108
- Samuel A, Asokan S, Geethapriya P. Caries status and salivary characteristics of South Indian school children. J Indian Assoc Public Health Dent. 2017;15(2):135.doi:10.4103/jiaphd.jiaphd_39_17
- Kim JH, Kim MA, Chae YK, Nam OH. Salivary characteristics and caries index among Korean children. Int J Environ Res Public Health. 2021;18(6):3118.doi:10.3390/ijerph18063118
- Kurek-Górecka A, et al. Influence of propolis on dental plaque reduction. Molecules. 2021;26(18):5516. doi:10.3390/molecules26185516
- Molaasadolah F, et al. Saliva composition, BMI and nutrition with molar caries. Open Access Maced J Med Sci. 2020;8(D):42–47.doi:10.3889/OAMJMS.2020.4062
- Ten Cate JM. In situ models of dental caries. Journal of Dental Research. 2001;80(10):1985–1989.doi:10.1177/00220345010800100901
- Stephan RM. Changes in hydrogen-ion concentration on tooth surfaces. Journal of the American Dental Association. 1940;27(5):718–723.doi:10.14219/jada.archive.1940.0064
- Anderson P, Hector MP, Rampersad MA. Critical pH in saliva. International Journal of Paediatric Dentistry. 2001;11(4):266–273.doi:/10.1046/j.1365-263X.2001.00272.x
- Loke C, et al. Factors affecting intra-oral pH. Journal of Oral Rehabilitation. 2016;43(10):778–785.doi:.1111/joor.12416
- Lippert F. An introduction to toothpaste. Monographs in Oral Science. 2013;23:1–14.doi:10.1159/000350465
- Bowen WH, Koo H. Biology of Streptococcus mutans glucosyltransferases. Caries Research. 2011;45(1):69–86.doi:10.1159/000324598
- Marsh PD, et al. Influence of diet on the oral microbiota. Journal of Dental Research. 2015;94(9):1180–1187. doi:10.1177/0022034515586549
- Fenoll-Palomares C, et al. Salivary flow rate, pH and buffer capacity. Revista Española de Enfermedades Digestivas. 2004;96:773–783.doi:10.4321/S1130-01082004001100003
- American Dental Association (ADA). Nutrition and Oral Health Guidelines. 2020.https://www.ada.org
- World Health Organization (WHO). Guideline: Sugars intake for adults and children. 2015.https://www.who.int/publications/i/item/WHO-NMH-NHD-15.2
- Jepsen S, et al. Prevention and control of dental caries and periodontal diseases. Journal of Clinical Periodontology. 2017;44(Suppl 18):S85–S93.doi:10.1111/jcpe.12687
- World Health Organization (WHO). Global Oral Health Status Report. 2022.https://www.who.int/publications/i/item/9789240061484.
References
Bell E. Strategy for the selection of scaffolds for tissue engineering. Tissue Eng. 1995 Jun 1;1(2):163-79. doi: 10.1007/s00586-008-0745-3.
Marsh PD. In sickness and in health—what does the oral microbiome mean to us? Clinical Oral Investigations. 2018;22(3):1137–1144.doi:10.1007/s00784-018-2464-2
Simón-Soro A, Mira A. Solving the etiology of dental caries. Trends in Microbiology.2015;23(2):76–82. doi:10.1016/j.tim.2014.10.010
Vellore G, Arzreanne AR. Saliva as a diagnostic tool for assessment of dental caries. Archives of Orofacial Sciences. 2006;1:57–59.https://publisher.uthm.edu.my/ojs/index.php/aos/article/view/289
Ruby JD, Goldner M. Nature of symbiosis in oral biofilms. Oral Diseases. 2007;13(1):11–18.doi:10.1111/j.1601-0825.2006.01305.x
Tanner ACR, et al. Microbiota of dental caries. Journal of Dental Research. 2016;95(6):624–630.doi:10.1177/0022034516644649
Bowen WH, Koo H. Biology of Streptococcus mutans–derived glucosyltransferases. Caries Research. 2011;45(1):69–86. doi:10.1159/000324598
Maria H, Fatmasari D. Relationship of saliva pH and DMF-T index in metadon housing therapy in Yogyakarta City. Jurnal Riset Kesehatan. 2020;9(1):28–32.doi:10.31983/jrk.v9i1.5641
Lin YTJ, Lin YT. Influence of dental plaque pH on caries status and salivary microflora in children following comprehensive dental care under general anesthesia. Journal of Dental Sciences. 2018;13(1):8–12.doi:10.1016/j.jds.2017.05.002
Ferrer MD, Pérez S, Lopez AL, et al. Evaluation of clinical, biochemical and microbiological markers related to dental caries. International Journal of Environmental Research and Public Health. 2021;18(11):6049.doi:10.3390/ijerph18116049
Hajishengallis E, Parsaei Y, Klein MI, Koo H. Advances in the microbial etiology and pathogenesis of early childhood caries. Molecular Oral Microbiology. 2017;32(1):24–34.doi:10.1111/omi.12152
Bowen WH, Burne RA, Wu H, Koo H. Oral biofilms: pathogens, matrix, and polymicrobial interactions in microenvironments. Trends in Microbiology. 2018;26(3):229–242. doi:10.1016/j.tim.2017.09.008
Saxena P, Bhatnagar M, Bansal R, et al. Association of dermatoglyphic patterns with DMFT score, salivary pH and plaque index score. Journal of Forensic Dental Sciences. 2022;12:81–88.doi:10.18311/jfds/12/2/2020.610
Aranibar Quiroz EM, et al. Relationship between plaque pH and different caries-associated variables. Caries Research. 2014;48(2):147–153.doi:10.1159/000355614
Scardina GA, Messina P. Good oral health and diet. Journal of Biomedicine and Biotechnology. 2012;2012:720692.doi:10.1155/2012/720692
Palmer CA, Boyd LD. Diet and nutrition in oral health. Journal of the California Dental Association. 2009;37(5):357–366.https://pubmed.ncbi.nlm.nih.gov/19473145
Nishida M, Grossi SG, Dunford RG, et al. Dietary vitamin C and the risk for periodontal disease. Journal of Periodontology. 2000;71(8):1215–1223.doi:10.1902/jop.2000
Duggal MS, van Loveren C. Dental considerations for dietary counselling. International Dental Journal. 2001;51(6):408–412.doi:10.1002/j.1875-595X.2001.tb00850.x
Bradshaw DJ, Lynch RJ. Diet and the microbial aetiology of dental caries. International Dental Journal. 2013;63(Suppl 2):64–72.doi:10.1111/idj.12082
Dawes C. Role of saliva and salivary diagnostics in oral health advancement. Journal of Dental Research. 2019;98(2):133–141.doi:10.1177/0022034518817108
Samuel A, Asokan S, Geethapriya P. Caries status and salivary characteristics of South Indian school children. J Indian Assoc Public Health Dent. 2017;15(2):135.doi:10.4103/jiaphd.jiaphd_39_17
Kim JH, Kim MA, Chae YK, Nam OH. Salivary characteristics and caries index among Korean children. Int J Environ Res Public Health. 2021;18(6):3118.doi:10.3390/ijerph18063118
Kurek-Górecka A, et al. Influence of propolis on dental plaque reduction. Molecules. 2021;26(18):5516. doi:10.3390/molecules26185516
Molaasadolah F, et al. Saliva composition, BMI and nutrition with molar caries. Open Access Maced J Med Sci. 2020;8(D):42–47.doi:10.3889/OAMJMS.2020.4062
Ten Cate JM. In situ models of dental caries. Journal of Dental Research. 2001;80(10):1985–1989.doi:10.1177/00220345010800100901
Stephan RM. Changes in hydrogen-ion concentration on tooth surfaces. Journal of the American Dental Association. 1940;27(5):718–723.doi:10.14219/jada.archive.1940.0064
Anderson P, Hector MP, Rampersad MA. Critical pH in saliva. International Journal of Paediatric Dentistry. 2001;11(4):266–273.doi:/10.1046/j.1365-263X.2001.00272.x
Loke C, et al. Factors affecting intra-oral pH. Journal of Oral Rehabilitation. 2016;43(10):778–785.doi:.1111/joor.12416
Lippert F. An introduction to toothpaste. Monographs in Oral Science. 2013;23:1–14.doi:10.1159/000350465
Bowen WH, Koo H. Biology of Streptococcus mutans glucosyltransferases. Caries Research. 2011;45(1):69–86.doi:10.1159/000324598
Marsh PD, et al. Influence of diet on the oral microbiota. Journal of Dental Research. 2015;94(9):1180–1187. doi:10.1177/0022034515586549
Fenoll-Palomares C, et al. Salivary flow rate, pH and buffer capacity. Revista Española de Enfermedades Digestivas. 2004;96:773–783.doi:10.4321/S1130-01082004001100003
American Dental Association (ADA). Nutrition and Oral Health Guidelines. 2020.https://www.ada.org
World Health Organization (WHO). Guideline: Sugars intake for adults and children. 2015.https://www.who.int/publications/i/item/WHO-NMH-NHD-15.2
Jepsen S, et al. Prevention and control of dental caries and periodontal diseases. Journal of Clinical Periodontology. 2017;44(Suppl 18):S85–S93.doi:10.1111/jcpe.12687
World Health Organization (WHO). Global Oral Health Status Report. 2022.https://www.who.int/publications/i/item/9789240061484.
